News

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Phillips family & friends continue their support of Bright Red

We have recently received another £1,500 in donations from Kath Phillips and her dear friends.

They raised this impressive sum through their regular Come Dine With Me event and taking on the Seaham Boxing Day dip.

We are extremely grateful for all they continue to do for our charity, we wouldn’t be able to do as much as we can without this kind of support. Every £1 truly makes a difference to blood cancer patients in the north.

Kath said “I want to say a big thank you to all our friends who have supported us as a family and the Bright Red Charity in memory of our son Christopher.”

Here are a few photos from their fundraising efforts!

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Newcastle business community celebrates another successful Oktoberfest

Property consultants Bilfinger GVA and international design practice, Ryder Architecture joined together once again to sponsor the third year annual Oktoberfest on 20 October at the new home of Wylam Brewery, in Exhibition Park, Newcastle.

The charity evening was attended by over 550 clients, professionals and members of the North East business community with all proceeds being split between two charities – Bright Red and Alzheimer’s Society.

Guests enjoyed a fun filled evening, sampling appropriate Oktoberfest food and drink whilst being entertained by local band, Groove Train.  There was a host of opportunities throughout the evening to take part in raffles, silent auctions and to buy specialist ales to further support these fantastic charities.

The event sponsors built upon last years’ success and raised over £2,000 for each charity on the evening.  Tom Baker of Bilfinger GVA commented, “It’s always a fantastic evening which attracts an amazing number of guests.  Most importantly we’ve raised lots of money two worthy charities”.

Jonathan Seebacher, architectural director at Ryder added, “We’re very proud to sponsor the evening again – the volume of people and money raised is testament to the North East property and development community.  We are delighted with the success of the event”.

This donation has been one of many from the team at Ryder. Ryder have been a major support to Bright Red over the years and we continue to be overwhelmed by all that they do. We are so thankful that they have been part of our journey and truly wouldn’t be where we are today without them.

Valentine Raffle

Our good friends at Daniel Farmshop in Wylam are hosting a Valentine’s Raffle to raise funds for us.

If you’ve ever been there you’ll know how fantastic the place is – if you haven’t been, you’re missing out!

Top prize is a Fenwicks spirit hamper worth over £100, runners up prizes include £50 gift hamper, £30 Meat voucher, Afternoon Tea for Two and a box of chocolates.

Tickets are £1 each. The draw takes place on Tuesday 14 February at noon.

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58th ASH Annual Meeting & Exposition

The 58th American Society of Hematology Meeting & Exposition took place over the 3rd – 6th December. We were delighted to be able to support Carmela Ciardullo with a Bright Red travel grant.

Carmela is a Research Associate at the Northern Insitute for Cancer Research, and was invited to present her abstract focusing on Chronic Lymphocytic Leukaemia.

Carmela said “ASH 2016 was an invaluable experience with thousands of delegates attending and numerous high quality oral and poster presentations. The excellent education program provided an opportunity to learn about research outside my normal field of interest and the scientific committee sessions as always provided up to the minute insights into a range of topics.

Of particular interest to me were both oral and poster presentations regarding novel MDM2 antagonists as a treatment options for patients with haematological malignancies. Christian Klein from Roche Innovation Center Zurich discussed their preclinical data demonstrating a strong anti-tumoral efficacy of combining the CD20 antibody obinutuzumab with the Bcl-2 inhibitor venetoclax and the MDM2 inhibitor RG7388. Their data showed that the triple combination of obinutuzumab with venetoclax and RG7388 can further improve outcome in two preclinical human wildtype p53 NHL tumor xenograft models, in particular regarding complete tumor remissions and long term response, and support the clinical investigation of this triple combination for the treatment of B cell malignancies.

Another study by William Pierceall showed that multiparametric flow cytometry MRD assessment is an early indication aligning with cCR in relapsed/refractory AML patients treated with RG7388. Further, assessment for association with progression-free survival indicated that the lowest quartile patients by MRD flow cytometry measurement (<1%) are likely to exhibit a pronounced survival benefit over those patients with higher detectable levels of MRD (>1%). As such, the data presented support inclusion of MRD assessment by flow cytometry as a prognostic indicator to provide guiding information for assignment of depth of AML patient response. This biomarker for diagnostic potential and prognostic indicator of survival-based outcomes should be monitored in future randomized clinical studies of RG7388.

Another study from MD Anderson Cancer Center reported the initial results of a Phase I trial aimed at characterizing the safety, tolerability, pharmacokinetic (PK), and pharmacodynamic (PD) profiles and preliminary efficacy of the MDM2 antagonist DS3032b in in patients with hematological malignancies.

However, a clinical challenge is that not all the tumors bearing wild-type TP53 are sensitive to MDM2 inhibition. In this respect, a group from MDM Anderson Cancer Center discovered novel gene profiling-based algorithms for predicting tumor sensitivity to MDM2 inhibition using DS-3032b, a novel potent MDM2 inhibitor, which is currently in early clinical trials.

Of particular interest to me were the presentations regarding novel treatment options for patients with chronic lymphocytic leukemia, as well as the numerous updates on CLL genomics and epigenomics. I also had the amazing opportunity to present my abstract entitled “The p53-MDM2 Antagonist RG7388 Activates p53 and Induces a Predominantly Pro-Apoptotic Gene Expression Signature in Chronic Lymphocytic Leukemia” and I had useful and positive feedback.

Overall ASH 2016 was an excellent experience. Many thanks to Bright Red for the Travel Award and for supporting my participation to this meeting.”

Custom Made Memory Bears For Sale In Aid Of Bright Red

We are very excited to have been given the opportunity to sell some custom made memory cushions and teddy bears.

 

These items are lovingly made from treasured items of clothing (E.G shirts or dressing gowns) creating an individual keepsake for the entire family.

 

  • The large bears are 16 inches tall and are £20 each.
  • Small bears are around 10 inches tall and are £15 each.
  • Cushions are £15 each and made to measure your own infill. Size of the cushion will very much depend on the sizing of the clothing. Most common sizes are 14 x 14, or 16 x 16.

 

It’s important to note that the bears are not suitable as toys.

 

As this is a new venture, we are limiting the first round of orders to the first 10 requests. If you would like to learn more about the bears/cushions, or would like to place an order please call Lisa on 07725 987195 or email Lisa@brightred.org.uk.

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Funds Raised In Memory Of Ken Stoker

screen-shot-2016-12-12-at-16-05-28We were deeply saddened to learn that Ken Stoker passed away recently.

Ken was a very brave man and extremely well thought of by everyone at the Freeman Hospital.

Ken’s family recently presented Bright Red with a cheque for £1,525. This sum was raised through donations given at Ken’s funeral. It’s a real testament to his character that so many of his friends and family gave so generously.

Our thoughts are with his family and friends at this difficult time.

Bright Red’s Wish Bracelets Now On Sale

We have a selection of handmade wish bracelets available for sale, with 100% of the profits going to Bright Red to help blood cancer patients in the north.

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   Make a wish upon this string,


You can wish for anything,


When the strong frays and breaks in two,


The Legend says your wish comes true!

There are variations with each charm – we have hearts, angel wings, and snowflakes in the adult size, on either a ‘wish for’ or a ‘kiss for’ backing card. The children’s bracelets all come with a holly charm.

Bracelets can be purchased direct from our EBay store.

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Christmas Raffle 2016

Our Christmas Raffle tickets are now on sale.

We have some wonderful prizes including :

  • A nights stay for two at The Village Hotel
  • A physiotherapy session at Gosforth Physio & Wellness
  • £100 Slaters voucher
  • A day at the races for two in an executive box
  • A tour for two at The Stadium of Light
  • £50 M&S Voucher
  • £100 As You Like it Vouchers……plus many, many more.

Tickets are £1 each & can be bought using the ‘Add to Cart’ link below. The draw will take place at noon on 19 December. Winners will be notified that afternoon.


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Lottery Licence No : LOTT194

Funds Raised In Memory Of Mary Hutchinson

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We recently received a donation of £371, raised in memory of Mary Hutchinson.

Mary was diagnosed back in 1984 and received treatment under Professor Proctor and Dr O’Brien. Mary was a long standing supporter of our charity and will be deeply missed by all who knew her.

Our thoughts are with Mary’s family and friends.

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Bright Red Agree To Fund New CNS Post At Sunderland Hospital

We have recently awarded Sunderland Royal Hospital £55,000 of funding to help employ an additional Clinical Nurse Specialist.

The additional CNS will enable the current team to offer a far superior service to haematology patients.

It would mean an increased amount of patients could meet with a CNS prior to starting chemotherapy. There would be a more streamlined pathway for patients attending the day unit who are unexpectedly unwell. With a planned rota between three Clinical Nurse Specialists available to review these patients on a daily basis, allowing for more rapid treatment and/or discharge home.

We are delighted to be in a position to fund another nursing post. As usual, we give thanks to our supporters for making this possible.

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